Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model

Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo. To avoid receptor interference and enable dual vector co-infection with MLV-RRV, we have...

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Detalles Bibliográficos
Autores principales: Chen, Shih-Han, Sun, Jui-Ming, Chen, Bing-Mao, Lin, Sheng-Che, Chang, Hao-Fang, Collins, Sara, Chang, Deching, Wu, Shu-Fen, Lu, Yin-Che, Wang, Weijun, Chen, Thomas C., Kasahara, Noriyuki, Wang, Hsin-Ell, Tai, Chien-Kuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073086/
https://www.ncbi.nlm.nih.gov/pubmed/32093290
http://dx.doi.org/10.3390/ijms21041433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073086/
https://www.ncbi.nlm.nih.gov/pubmed/32093290
http://dx.doi.org/10.3390/ijms21041433

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