Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD

In inflammatory bowel disease (IBD), the intestinal epithelium is characterized by increased permeability both in active disease and remission states. The genetic underpinnings of this increased intestinal permeability are largely unstudied, in part due to a lack of appropriate modelling systems. Ou...

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Detalles Bibliográficos
Autores principales: Gleeson, John P., Estrada, Hannah Q., Yamashita, Michifumi, Svendsen, Clive N., Targan, Stephan R., Barrett, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073090/
https://www.ncbi.nlm.nih.gov/pubmed/32093254
http://dx.doi.org/10.3390/ijms21041438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073090/
https://www.ncbi.nlm.nih.gov/pubmed/32093254
http://dx.doi.org/10.3390/ijms21041438

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