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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD
In inflammatory bowel disease (IBD), the intestinal epithelium is characterized by increased permeability both in active disease and remission states. The genetic underpinnings of this increased intestinal permeability are largely unstudied, in part due to a lack of appropriate modelling systems. Ou...
Autores principales: | Gleeson, John P., Estrada, Hannah Q., Yamashita, Michifumi, Svendsen, Clive N., Targan, Stephan R., Barrett, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073090/ https://www.ncbi.nlm.nih.gov/pubmed/32093254 http://dx.doi.org/10.3390/ijms21041438 |
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