Hypercapnia Impairs Na,K-ATPase Function by Inducing Endoplasmic Reticulum Retention of the β-Subunit of the Enzyme in Alveolar Epithelial Cells

Alveolar edema, impaired alveolar fluid clearance, and elevated CO(2) levels (hypercapnia) are hallmarks of the acute respiratory distress syndrome (ARDS). This study investigated how hypercapnia affects maturation of the Na,K-ATPase (NKA), a key membrane transporter, and a cell adhesion molecule in...

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Detalles Bibliográficos
Autores principales: Kryvenko, Vitalii, Wessendorf, Miriam, Morty, Rory E., Herold, Susanne, Seeger, Werner, Vagin, Olga, Dada, Laura A., Sznajder, Jacob I., Vadász, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073107/
https://www.ncbi.nlm.nih.gov/pubmed/32098115
http://dx.doi.org/10.3390/ijms21041467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073107/
https://www.ncbi.nlm.nih.gov/pubmed/32098115
http://dx.doi.org/10.3390/ijms21041467

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