Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup(®) Dietary Supplement: Role of Green Tea Catechins

Epigallocatechin gallate (EGCG) is an inhibitor of DYRK1A, a serine/threonine kinase considered to be a major contributor of cognitive dysfunctions in Down syndrome (DS). Two clinical trials in adult patients with DS have shown the safety and efficacy to improve cognitive phenotypes using commercial...

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Detalles Bibliográficos
Autores principales: Gu, Yuchen, Moroy, Gautier, Paul, Jean-Louis, Rebillat, Anne-Sophie, Dierssen, Mara, de la Torre, Rafael, Cieuta-Walti, Cécile, Dairou, Julien, Janel, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073110/
https://www.ncbi.nlm.nih.gov/pubmed/32092951
http://dx.doi.org/10.3390/ijms21041404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073110/
https://www.ncbi.nlm.nih.gov/pubmed/32092951
http://dx.doi.org/10.3390/ijms21041404

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