Attenuation of Hypertrophy in Human MSCs via Treatment with a Retinoic Acid Receptor Inverse Agonist

In vitro chondrogenically differentiated mesenchymal stem cells (MSCs) have a tendency to undergo hypertrophy, mirroring the fate of transient “chondrocytes” in the growth plate. As hypertrophy would result in ossification, this fact limits their use in cartilage tissue engineering applications. Dur...

Descripción completa

Detalles Bibliográficos
Autores principales: Riedl, Moritz, Witzmann, Christina, Koch, Matthias, Lang, Siegmund, Kerschbaum, Maximilian, Baumann, Florian, Krutsch, Werner, Docheva, Denitsa, Alt, Volker, Pfeifer, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073129/
https://www.ncbi.nlm.nih.gov/pubmed/32093330
http://dx.doi.org/10.3390/ijms21041444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073129/
https://www.ncbi.nlm.nih.gov/pubmed/32093330
http://dx.doi.org/10.3390/ijms21041444

Ejemplares similares