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PTEN Expression as a Complementary Biomarker for Mismatch Repair Testing in Breast Cancer

Mismatch repair (MMR) analysis in breast cancer may help to inform immunotherapy decisions but it lacks breast-specific guidelines. Unlike in other neoplasms, MMR protein loss shows intra-tumor heterogeneity and it is not mirrored by microsatellite instability in the breast. Additional biomarkers ca...

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Detalles Bibliográficos
Autores principales: Lopez, Gianluca, Noale, Marianna, Corti, Chiara, Gaudioso, Gabriella, Sajjadi, Elham, Venetis, Konstantinos, Gambini, Donatella, Runza, Letterio, Costanza, Jole, Pesenti, Chiara, Grossi, Francesco, Maggi, Stefania, Ferrero, Stefano, Bosari, Silvano, Fusco, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073136/
https://www.ncbi.nlm.nih.gov/pubmed/32098071
http://dx.doi.org/10.3390/ijms21041461