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Plasma Next Generation Sequencing and Droplet Digital-qPCR-Based Quantification of Circulating Cell-Free RNA for Noninvasive Early Detection of Cancer

Early detection of cancer holds high promise for reducing cancer-related mortality. Detection of circulating tumor-specific nucleic acids holds promise, but sensitivity and specificity issues remain with current technology. We studied cell-free RNA (cfRNA) in patients with non-small cell lung cancer...

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Detalles Bibliográficos
Autores principales: Metzenmacher, Martin, Váraljai, Renáta, Hegedüs, Balazs, Cima, Igor, Forster, Jan, Schramm, Alexander, Scheffler, Björn, Horn, Peter A., Klein, Christoph A., Szarvas, Tibor, Reis, Hennig, Bielefeld, Nicola, Roesch, Alexander, Aigner, Clemens, Kunzmann, Volker, Wiesweg, Marcel, Siveke, Jens T., Schuler, Martin, Lueong, Smiths S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073169/
https://www.ncbi.nlm.nih.gov/pubmed/32033141
http://dx.doi.org/10.3390/cancers12020353