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Detection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma Patients
DNA methylation plays an important role in cancer development. Cancer cells exhibit two types of DNA methylation alteration: site-specific hypermethylation at promoter of oncosuppressor genes and global DNA hypomethylation. This study evaluated the methylation patterns of long interspersed nuclear e...
Autores principales: | Boldrin, Elisa, Curtarello, Matteo, Dallan, Marco, Alfieri, Rita, Realdon, Stefano, Fassan, Matteo, Saggioro, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073170/ https://www.ncbi.nlm.nih.gov/pubmed/32102481 http://dx.doi.org/10.3390/ijms21041547 |
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