Detection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma Patients

DNA methylation plays an important role in cancer development. Cancer cells exhibit two types of DNA methylation alteration: site-specific hypermethylation at promoter of oncosuppressor genes and global DNA hypomethylation. This study evaluated the methylation patterns of long interspersed nuclear e...

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Detalles Bibliográficos
Autores principales: Boldrin, Elisa, Curtarello, Matteo, Dallan, Marco, Alfieri, Rita, Realdon, Stefano, Fassan, Matteo, Saggioro, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073170/
https://www.ncbi.nlm.nih.gov/pubmed/32102481
http://dx.doi.org/10.3390/ijms21041547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073170/
https://www.ncbi.nlm.nih.gov/pubmed/32102481
http://dx.doi.org/10.3390/ijms21041547

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