GPER Activation Inhibits Cancer Cell Mechanotransduction and Basement Membrane Invasion via RhoA

The invasive properties of cancer cells are intimately linked to their mechanical phenotype, which can be regulated by intracellular biochemical signalling. Cell contractility, induced by mechanotransduction of a stiff fibrotic matrix, and the epithelial–mesenchymal transition (EMT) promote invasion...

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Detalles Bibliográficos
Autores principales: Rice, Alistair, Cortes, Ernesto, Lachowski, Dariusz, Oertle, Philipp, Matellan, Carlos, Thorpe, Stephen D., Ghose, Ritobrata, Wang, Haiyun, Lee, David A., Plodinec, Marija, del Río Hernández, Armando E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073197/
https://www.ncbi.nlm.nih.gov/pubmed/31991740
http://dx.doi.org/10.3390/cancers12020289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073197/
https://www.ncbi.nlm.nih.gov/pubmed/31991740
http://dx.doi.org/10.3390/cancers12020289

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