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A Curcumin Derivative Activates TFEB and Protects Against Parkinsonian Neurotoxicity in Vitro
TFEB (transcription factor EB), which is a master regulator of autophagy and lysosome biogenesis, is considered to be a new therapeutic target for Parkinson’s disease (PD). However, only several small-molecule TFEB activators have been discovered and their neuroprotective effects in PD are unclear....
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073207/ https://www.ncbi.nlm.nih.gov/pubmed/32098449 http://dx.doi.org/10.3390/ijms21041515 |