CG200745, a Novel HDAC Inhibitor, Attenuates Kidney Fibrosis in a Murine Model of Alport Syndrome

Histone deacetylases have been a target of therapy for organ fibrosis. Here, we report the protective effect of CG200745 (CG), a novel histone deacetylase inhibitor, on tubulointerstitial fibrosis in Col4a3(−/−) mice, a murine model of Alport syndrome. Morphological analyses revealed CG treatment ma...

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Detalles Bibliográficos
Autores principales: Suh, Sang Heon, Choi, Hong Sang, Kim, Chang Seong, Kim, In Jin, Cha, Hyunju, Cho, Joong Myung, Ma, Seong Kwon, Kim, Soo Wan, Bae, Eun Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073208/
https://www.ncbi.nlm.nih.gov/pubmed/32098220
http://dx.doi.org/10.3390/ijms21041473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073208/
https://www.ncbi.nlm.nih.gov/pubmed/32098220
http://dx.doi.org/10.3390/ijms21041473

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