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Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress

Islet dysfunction mediated by oxidative and mitochondrial stress contributes to the development of type 1 and 2 diabetes. Acetate and butyrate, produced by gut microbiota via fermentation, have been shown to protect against oxidative and mitochondrial stress in many cell types, but their effect on p...

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Detalles Bibliográficos
Autores principales: Hu, Shuxian, Kuwabara, Rei, de Haan, Bart J., Smink, Alexandra M., de Vos, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073211/
https://www.ncbi.nlm.nih.gov/pubmed/32102422
http://dx.doi.org/10.3390/ijms21041542