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Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress
Islet dysfunction mediated by oxidative and mitochondrial stress contributes to the development of type 1 and 2 diabetes. Acetate and butyrate, produced by gut microbiota via fermentation, have been shown to protect against oxidative and mitochondrial stress in many cell types, but their effect on p...
Autores principales: | Hu, Shuxian, Kuwabara, Rei, de Haan, Bart J., Smink, Alexandra M., de Vos, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073211/ https://www.ncbi.nlm.nih.gov/pubmed/32102422 http://dx.doi.org/10.3390/ijms21041542 |
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