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Local rewiring of genome–nuclear lamina interactions by transcription

Transcriptionally inactive genes are often positioned at the nuclear lamina (NL), as part of large lamina‐associated domains (LADs). Activation of such genes is often accompanied by repositioning toward the nuclear interior. How this process works and how it impacts flanking chromosomal regions are...

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Detalles Bibliográficos
Autores principales: Brueckner, Laura, Zhao, Peiyao A, van Schaik, Tom, Leemans, Christ, Sima, Jiao, Peric‐Hupkes, Daniel, Gilbert, David M, van Steensel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073462/
https://www.ncbi.nlm.nih.gov/pubmed/32080885
http://dx.doi.org/10.15252/embj.2019103159