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Local rewiring of genome–nuclear lamina interactions by transcription
Transcriptionally inactive genes are often positioned at the nuclear lamina (NL), as part of large lamina‐associated domains (LADs). Activation of such genes is often accompanied by repositioning toward the nuclear interior. How this process works and how it impacts flanking chromosomal regions are...
Autores principales: | Brueckner, Laura, Zhao, Peiyao A, van Schaik, Tom, Leemans, Christ, Sima, Jiao, Peric‐Hupkes, Daniel, Gilbert, David M, van Steensel, Bas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073462/ https://www.ncbi.nlm.nih.gov/pubmed/32080885 http://dx.doi.org/10.15252/embj.2019103159 |
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