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3D Culture System for Liver Tissue Mimicking Hepatic Plates for Improvement of Human Hepatocyte (C3A) Function and Polarity

In vitro 3D hepatocyte culture constitutes a core aspect of liver tissue engineering. However, conventional 3D cultures are unable to maintain hepatocyte polarity, functional phenotype, or viability. Here, we employed microfluidic chip technology combined with natural alginate hydrogels to construct...

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Detalles Bibliográficos
Autores principales: Jia, Zhidong, Cheng, Yuan, Jiang, Xinan, Zhang, Chengyan, Wang, Gaoshang, Xu, Jiecheng, Li, Yang, Peng, Qing, Gao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073475/
https://www.ncbi.nlm.nih.gov/pubmed/32190673
http://dx.doi.org/10.1155/2020/6354183