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Aloe-Emodin Induces Breast Tumor Cell Apoptosis through Upregulation of miR-15a/miR-16-1 That Suppresses BCL2

PURPOSE: Aloe-emodin (AE) is a natural compound derived from aloe vera and palmatum rhubarb and shows anticancer activities in various cancers. Bcl-2 family is the main regulator of cell death or cell survival. This study describes the effects of AE on proliferation of breast tumor (BT) cells. METHO...

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Detalles Bibliográficos
Autores principales: Jiang, Xuefeng, Liu, Yusheng, Zhang, Guijuan, Lin, Shujun, Wu, Jieyan, Yan, Xianxin, Ma, Yi, Ma, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073502/
https://www.ncbi.nlm.nih.gov/pubmed/32190086
http://dx.doi.org/10.1155/2020/5108298