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Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1

Neurofibromatosis type 1 (NF1) is a monogenic syndrome that gives rise to numerous symptoms including cognitive impairment, skeletal abnormalities, and growth of benign nerve sheath tumors. Nearly all NF1 patients develop cutaneous neurofibromas (cNFs), which occur on the skin surface, whereas 40–60...

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Detalles Bibliográficos
Autores principales: Banerjee, Jineta, Allaway, Robert J, Taroni, Jaclyn N, Baker, Aaron, Zhang, Xiaochun, Moon, Chang In, Pratilas, Christine A, Blakeley, Jaishri O, Guinney, Justin, Hirbe, Angela, Greene, Casey S, Gosline, Sara JC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073563/
https://www.ncbi.nlm.nih.gov/pubmed/32098059
http://dx.doi.org/10.3390/genes11020226