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Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1
Neurofibromatosis type 1 (NF1) is a monogenic syndrome that gives rise to numerous symptoms including cognitive impairment, skeletal abnormalities, and growth of benign nerve sheath tumors. Nearly all NF1 patients develop cutaneous neurofibromas (cNFs), which occur on the skin surface, whereas 40–60...
Autores principales: | Banerjee, Jineta, Allaway, Robert J, Taroni, Jaclyn N, Baker, Aaron, Zhang, Xiaochun, Moon, Chang In, Pratilas, Christine A, Blakeley, Jaishri O, Guinney, Justin, Hirbe, Angela, Greene, Casey S, Gosline, Sara JC |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073563/ https://www.ncbi.nlm.nih.gov/pubmed/32098059 http://dx.doi.org/10.3390/genes11020226 |
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