Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What’s Next

Endonuclease-mediated genome editing technologies, most notably CRISPR/Cas9, have revolutionized animal genetics by allowing for precise genome editing directly through embryo manipulations. As endonuclease-mediated model generation became commonplace, large fragment knock-in remained one of the mos...

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Detalles Bibliográficos
Autores principales: Erwood, Steven, Gu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073597/
https://www.ncbi.nlm.nih.gov/pubmed/32013077
http://dx.doi.org/10.3390/genes11020140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073597/
https://www.ncbi.nlm.nih.gov/pubmed/32013077
http://dx.doi.org/10.3390/genes11020140

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