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Identification of Functional Transcriptional Binding Sites within Chicken Abcg2 Gene Promoter and Screening Its Regulators

Breast cancer resistance protein (BCRP), an ATP-binding cassette (ABC) half transporter encoded by the Abcg2 gene, is reported to influence the pharmacokinetics of substrate drugs during clinical therapy. The aim of this study was to clarify the mechanisms that regulate the transcription of the chic...

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Detalles Bibliográficos
Autores principales: Zhang, Yujuan, Huang, Jinhu, Li, Xiangxiu, Fang, Ci, Wang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073639/
https://www.ncbi.nlm.nih.gov/pubmed/32050731
http://dx.doi.org/10.3390/genes11020186