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Photoprotective Activity of Topsentin, A Bis(Indole) Alkaloid from the Marine Sponge Spongosorites genitrix, by Regulation of COX-2 and Mir-4485 Expression in UVB-Irradiated Human Keratinocyte Cells

Skin is an important barrier to protect the body from environmental stress. However, exposure to ultraviolet radiation (UV) and various environmental oxidative stresses can cause skin inflammation. Cyclooxygenase-2 (COX-2) is an inducible enzyme that mediates the formation of prostaglandin E(2) (PGE...

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Detalles Bibliográficos
Autores principales: Hwang, Jiyoung, Kim, Donghwa, Park, Jae Sung, Park, Hyen Joo, Shin, Jongheon, Lee, Sang Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073676/
https://www.ncbi.nlm.nih.gov/pubmed/32013063
http://dx.doi.org/10.3390/md18020087