p53 CRISPR Deletion Affects DNA Structure and Nuclear Architecture

The TP53 gene is a key tumor suppressor. Although the tumor suppressor p53 was one of the first to be characterized as a transcription factor, with its main function potentiated by its interaction with DNA, there are still many unresolved questions about its mechanism of action. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Rangel-Pozzo, Aline, Booth, Samuel, Yu, Pak Lok Ivan, Singh, Madhurendra, Selivanova, Galina, Mai, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073688/
https://www.ncbi.nlm.nih.gov/pubmed/32098416
http://dx.doi.org/10.3390/jcm9020598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073688/
https://www.ncbi.nlm.nih.gov/pubmed/32098416
http://dx.doi.org/10.3390/jcm9020598

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