rAAV-Mediated Cochlear Gene Therapy: Prospects and Challenges for Clinical Application

Over the last decade, pioneering molecular gene therapy for inner-ear disorders have achieved experimental hearing improvements after a single local or systemic injection of adeno-associated, virus-derived vectors (rAAV for recombinant AAV) encoding an extra copy of a normal gene, or ribozymes used...

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Detalles Bibliográficos
Autores principales: Blanc, Fabian, Mondain, Michel, Bemelmans, Alexis-Pierre, Affortit, Corentin, Puel, Jean-Luc, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073754/
https://www.ncbi.nlm.nih.gov/pubmed/32098144
http://dx.doi.org/10.3390/jcm9020589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073754/
https://www.ncbi.nlm.nih.gov/pubmed/32098144
http://dx.doi.org/10.3390/jcm9020589

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