Potential Tools for Eradicating HIV Reservoirs in the Brain: Development of Trojan Horse Prodrugs for the Inhibition of P-Glycoprotein with Anti-HIV-1 Activity

[Image: see text] Combination antiretroviral therapy is the mainstay of HIV treatment, lowering plasma viral levels below detection. However, eradication of HIV is a major challenge due to cellular and anatomical viral reservoirs that are often protected from treatment by efflux transporters, such a...

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Detalles Bibliográficos
Autores principales: Agrawal, Neha, Rowe, Jennifer, Lan, Jie, Yu, Qigui, Hrycyna, Christine A., Chmielewski, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073916/
https://www.ncbi.nlm.nih.gov/pubmed/31505928
http://dx.doi.org/10.1021/acs.jmedchem.9b00779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073916/
https://www.ncbi.nlm.nih.gov/pubmed/31505928
http://dx.doi.org/10.1021/acs.jmedchem.9b00779

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