The Functional Consequences of Eukaryotic Topoisomerase 1 Interaction with G-Quadruplex DNA

Topoisomerase I in eukaryotic cells is an important regulator of DNA topology. Its catalytic function is to remove positive or negative superhelical tension by binding to duplex DNA, creating a reversible single-strand break, and finally religating the broken strand. Proper maintenance of DNA topolo...

Descripción completa

Detalles Bibliográficos
Autores principales: Berroyer, Alexandra, Kim, Nayun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073998/
https://www.ncbi.nlm.nih.gov/pubmed/32059547
http://dx.doi.org/10.3390/genes11020193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073998/
https://www.ncbi.nlm.nih.gov/pubmed/32059547
http://dx.doi.org/10.3390/genes11020193

Ejemplares similares