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Dysregulation of Calcium Handling in Duchenne Muscular Dystrophy-Associated Dilated Cardiomyopathy: Mechanisms and Experimental Therapeutic Strategies

Duchenne muscular dystrophy (DMD) is an X-linked recessive disease resulting in the loss of dystrophin, a key cytoskeletal protein in the dystrophin-glycoprotein complex. Dystrophin connects the extracellular matrix with the cytoskeleton and stabilizes the sarcolemma. Cardiomyopathy is prominent in...

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Detalles Bibliográficos
Autores principales: Law, Michelle L., Cohen, Houda, Martin, Ashley A., Angulski, Addeli Bez Batti, Metzger, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074327/
https://www.ncbi.nlm.nih.gov/pubmed/32075145
http://dx.doi.org/10.3390/jcm9020520