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Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane
A clarification method was proposed to ameliorate the technological quality of fruit juices by preserving bioactive compounds. This study evaluated the in vitro antioxidant and hypoglycemic activities and the in vivo effects of Punica granatum L. natural (NJ) and clarified (CJ) juice by polyvinylide...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074394/ https://www.ncbi.nlm.nih.gov/pubmed/32102311 http://dx.doi.org/10.3390/foods9020242 |
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author | Morittu, Valeria Maria Mastellone, Vincenzo Tundis, Rosa Loizzo, Monica Rosa Tudisco, Raffaella Figoli, Alberto Cassano, Alfredo Musco, Nadia Britti, Domenico Infascelli, Federico Lombardi, Pietro |
author_facet | Morittu, Valeria Maria Mastellone, Vincenzo Tundis, Rosa Loizzo, Monica Rosa Tudisco, Raffaella Figoli, Alberto Cassano, Alfredo Musco, Nadia Britti, Domenico Infascelli, Federico Lombardi, Pietro |
author_sort | Morittu, Valeria Maria |
collection | PubMed |
description | A clarification method was proposed to ameliorate the technological quality of fruit juices by preserving bioactive compounds. This study evaluated the in vitro antioxidant and hypoglycemic activities and the in vivo effects of Punica granatum L. natural (NJ) and clarified (CJ) juice by polyvinylidene fluoride (PVDF) hollow fiber membrane. CJ was more active as an antioxidant and as a α-glucosidase inhibitor than NJ. Mice were orally gavaged with water (Control), NJ, and CJ for 28 days. NJ group showed significant decrease of alanine aminotransferase, aspartate amino transferase, and creatine-phosphokinase. CJ administration was associated with urea, creatine-phosphokinase, and triglycerides values significantly lower with respect to the control. Oxidative status was ameliorated with CJ administration, showing a reactive oxygen metabolites (d-ROMs) reduction of 32% and a biological antioxidant potential (BAP) boosting of 23% compared to the control, whereas NJ did not show a similar effect. Results confirmed the beneficial properties of pomegranate juice, showing that membrane clarification may enhance such effects in terms of antioxidant activity. |
format | Online Article Text |
id | pubmed-7074394 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70743942020-03-20 Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane Morittu, Valeria Maria Mastellone, Vincenzo Tundis, Rosa Loizzo, Monica Rosa Tudisco, Raffaella Figoli, Alberto Cassano, Alfredo Musco, Nadia Britti, Domenico Infascelli, Federico Lombardi, Pietro Foods Article A clarification method was proposed to ameliorate the technological quality of fruit juices by preserving bioactive compounds. This study evaluated the in vitro antioxidant and hypoglycemic activities and the in vivo effects of Punica granatum L. natural (NJ) and clarified (CJ) juice by polyvinylidene fluoride (PVDF) hollow fiber membrane. CJ was more active as an antioxidant and as a α-glucosidase inhibitor than NJ. Mice were orally gavaged with water (Control), NJ, and CJ for 28 days. NJ group showed significant decrease of alanine aminotransferase, aspartate amino transferase, and creatine-phosphokinase. CJ administration was associated with urea, creatine-phosphokinase, and triglycerides values significantly lower with respect to the control. Oxidative status was ameliorated with CJ administration, showing a reactive oxygen metabolites (d-ROMs) reduction of 32% and a biological antioxidant potential (BAP) boosting of 23% compared to the control, whereas NJ did not show a similar effect. Results confirmed the beneficial properties of pomegranate juice, showing that membrane clarification may enhance such effects in terms of antioxidant activity. MDPI 2020-02-24 /pmc/articles/PMC7074394/ /pubmed/32102311 http://dx.doi.org/10.3390/foods9020242 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Morittu, Valeria Maria Mastellone, Vincenzo Tundis, Rosa Loizzo, Monica Rosa Tudisco, Raffaella Figoli, Alberto Cassano, Alfredo Musco, Nadia Britti, Domenico Infascelli, Federico Lombardi, Pietro Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane |
title | Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane |
title_full | Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane |
title_fullStr | Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane |
title_full_unstemmed | Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane |
title_short | Antioxidant, Biochemical, and In-Life Effects of Punica granatum L. Natural Juice vs. Clarified Juice by Polyvinylidene Fluoride Membrane |
title_sort | antioxidant, biochemical, and in-life effects of punica granatum l. natural juice vs. clarified juice by polyvinylidene fluoride membrane |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074394/ https://www.ncbi.nlm.nih.gov/pubmed/32102311 http://dx.doi.org/10.3390/foods9020242 |
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