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Pathogenic Mitochondria DNA Mutations: Current Detection Tools and Interventions

Mitochondria are best known for their role in energy production, and they are the only mammalian organelles that contain their own genomes. The mitochondrial genome mutation rate is reported to be 10–17 times higher compared to nuclear genomes as a result of oxidative damage caused by reactive oxyge...

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Detalles Bibliográficos
Autores principales: Mustafa, Mohd Fazirul, Fakurazi, Sharida, Abdullah, Maizaton Atmadini, Maniam, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074468/
https://www.ncbi.nlm.nih.gov/pubmed/32059522
http://dx.doi.org/10.3390/genes11020192