Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy

Alzheimer’s disease (AD) is characterized, amongst other features, by the pathologic accumulation of abnormally phosphorylated tau filaments in neurons that lead to neurofibrillary tangles. However, the molecular mechanisms by which the abnormal processing of tau leads to neurodegeneration and cogni...

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Detalles Bibliográficos
Autores principales: Tondo, Mireia, Wasek, Brandi, Escola-Gil, Joan Carles, de Gonzalo-Calvo, David, Harmon, Clinton, Arning, Erland, Bottiglieri, Teodoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074477/
https://www.ncbi.nlm.nih.gov/pubmed/32075035
http://dx.doi.org/10.3390/metabo10020069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074477/
https://www.ncbi.nlm.nih.gov/pubmed/32075035
http://dx.doi.org/10.3390/metabo10020069

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