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Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

Inflammatory cells contribute to irreversible damage in pulmonary arterial hypertension (PAH). We hypothesized that in PAH, dysfunctional BMPR2 signaling in macrophages contributes to pulmonary vascular injury and phenotypic changes via proinflammatory cytokine production. Studies were conducted in:...

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Detalles Bibliográficos
Autores principales: West, James, Chen, Xinping, Yan, Ling, Gladson, Santhi, Loyd, James, Rizwan, Hamid, Talati, Megha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074495/
https://www.ncbi.nlm.nih.gov/pubmed/31124398
http://dx.doi.org/10.1177/2045894019856483