Cargando…
Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension
Inflammatory cells contribute to irreversible damage in pulmonary arterial hypertension (PAH). We hypothesized that in PAH, dysfunctional BMPR2 signaling in macrophages contributes to pulmonary vascular injury and phenotypic changes via proinflammatory cytokine production. Studies were conducted in:...
Autores principales: | West, James, Chen, Xinping, Yan, Ling, Gladson, Santhi, Loyd, James, Rizwan, Hamid, Talati, Megha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074495/ https://www.ncbi.nlm.nih.gov/pubmed/31124398 http://dx.doi.org/10.1177/2045894019856483 |
Ejemplares similares
-
BMPR2 expression is suppressed by signaling through the estrogen receptor
por: Austin, Eric D, et al.
Publicado: (2012) -
Copy-number variation in BMPR2 is not associated with the pathogenesis of pulmonary arterial hypertension
por: Johnson, Jennifer A, et al.
Publicado: (2009) -
The genetics of pulmonary arterial hypertension in the post-BMPR2 era
por: Fessel, Joshua P., et al.
Publicado: (2011) -
A potential adverse role for leptin and cardiac leptin receptor in the right ventricle in pulmonary arterial hypertension: effect of metformin is BMPR2 mutation-specific
por: Talati, Megha, et al.
Publicado: (2023) -
Overexpression of Msx1 in Mouse Lung Leads to Loss of Pulmonary Vessels Following Vascular Hypoxic Injury
por: West, James, et al.
Publicado: (2021)