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Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer

BACKGROUND: Sonic hedgehog (Shh) and Nrf2 play a critical role in chemotherapeutic resistance. These two genes have been found to be dysregulated in head and neck squamous cell carcinomas (HNSCC). The purpose of this study was to analyze the expression, function and clinical prognostic relationship...

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Detalles Bibliográficos
Autores principales: Noman, Abu Shadat M., Parag, Rashed R., Rashid, Muhammad I., Rahman, Mohammad Z., Chowdhury, Ali A., Sultana, Afrin, Jerin, Chandsultana, Siddiqua, Ayesha, Rahman, Lutfur, Shirin, Afsana, Nayeem, Junayed, Mahmud, Reaz, Akther, Sonam, Shil, Rajib K., Hossain, Ikram, Alam, Sharmin, Chowdhury, Arfina, Basher, Shabnam B., Hasan, Abul, Bithy, Shammy, Aklima, Jannatul, Rahman, Mizanur, Chowdhury, Nabila, Banu, Tahmina, Karakas, Bedri, Yeger, Herman, Farhat, Walid A., Islam, Syed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074584/
https://www.ncbi.nlm.nih.gov/pubmed/32206093
http://dx.doi.org/10.1177/1758835920911229