Estrogen metabolites in a small cohort of patients with idiopathic pulmonary arterial hypertension

Increased risk and severity of idiopathic pulmonary arterial hypertension (iPAH) is associated with elevated estradiol in men and postmenopausal women. Pulmonary arteries synthesise estradiol via aromatase and metabolise it via CYP1B1 to mitogenic metabolites; SNPs in aromatase and CYP1B1 have been...

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Detalles Bibliográficos
Autores principales: Denver, Nina, Homer, Natalie Z.M., Andrew, Ruth, Harvey, Katie Y., Morrell, Nicholas, Austin, Eric D., MacLean, Margaret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074610/
https://www.ncbi.nlm.nih.gov/pubmed/32206305
http://dx.doi.org/10.1177/2045894020908783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074610/
https://www.ncbi.nlm.nih.gov/pubmed/32206305
http://dx.doi.org/10.1177/2045894020908783

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