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Functions of Enyolreductase (ER) Domains of PKS Cluster in Lipid Synthesis and Enhancement of PUFAs Accumulation in Schizochytrium limacinum SR21 Using Triclosan as a Regulator of ER

The polyketide synthase (PKS) cluster genes are supposed to synthesize polyunsaturated fatty acids (PUFAs) in S. limacinum. In this study, two enyolreductase (ER) genes located on PKS cluster were knocked out through homologous recombination to explore their functions. The knock-out of OrfB-ER (loca...

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Detalles Bibliográficos
Autores principales: Ling, Xueping, Zhou, Hao, Yang, Qinghua, Yu, Shengyang, Li, Jun, Li, Zhipeng, He, Ning, Chen, Cuixue, Lu, Yinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074904/
https://www.ncbi.nlm.nih.gov/pubmed/32098234
http://dx.doi.org/10.3390/microorganisms8020300