Discovery of Two Brominated Oxindole Alkaloids as Staphylococcal DNA Gyrase and Pyruvate Kinase Inhibitors via Inverse Virtual Screening

In the present study, a small marine-derived natural products library was assessed for antibacterial potential. Among 36 isolated compounds, a number of bis-indole derivatives exhibited growth-inhibitory activity towards Gram-positive strains (Bacillus subtilis and multidrug-resistant Staphylococcus...

Descripción completa

Detalles Bibliográficos
Autores principales: Sayed, Ahmed M., Alhadrami, Hani A., El-Hawary, Seham S., Mohammed, Rabab, Hassan, Hossam M., Rateb, Mostafa E., Abdelmohsen, Usama Ramadan, Bakeer, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074965/
https://www.ncbi.nlm.nih.gov/pubmed/32093370
http://dx.doi.org/10.3390/microorganisms8020293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074965/
https://www.ncbi.nlm.nih.gov/pubmed/32093370
http://dx.doi.org/10.3390/microorganisms8020293

Ejemplares similares