Proteomic and Transcriptional Profiles of Human Stem Cell-Derived β Cells Following Enteroviral Challenge

Enteroviral infections are implicated in islet autoimmunity and type 1 diabetes (T1D) pathogenesis. Significant β-cell stress and damage occur with viral infection, leading to cells that are dysfunctional and vulnerable to destruction. Human stem cell-derived β (SC-β) cells are insulin-producing cel...

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Detalles Bibliográficos
Autores principales: Nyalwidhe, Julius O., Jurczyk, Agata, Satish, Basanthi, Redick, Sambra, Qaisar, Natasha, Trombly, Melanie I., Vangala, Pranitha, Racicot, Riccardo, Bortell, Rita, Harlan, David M., Greiner, Dale L., Brehm, Michael A., Nadler, Jerry L., Wang, Jennifer P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074978/
https://www.ncbi.nlm.nih.gov/pubmed/32093375
http://dx.doi.org/10.3390/microorganisms8020295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074978/
https://www.ncbi.nlm.nih.gov/pubmed/32093375
http://dx.doi.org/10.3390/microorganisms8020295

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