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Proteomic and Transcriptional Profiles of Human Stem Cell-Derived β Cells Following Enteroviral Challenge
Enteroviral infections are implicated in islet autoimmunity and type 1 diabetes (T1D) pathogenesis. Significant β-cell stress and damage occur with viral infection, leading to cells that are dysfunctional and vulnerable to destruction. Human stem cell-derived β (SC-β) cells are insulin-producing cel...
Autores principales: | Nyalwidhe, Julius O., Jurczyk, Agata, Satish, Basanthi, Redick, Sambra, Qaisar, Natasha, Trombly, Melanie I., Vangala, Pranitha, Racicot, Riccardo, Bortell, Rita, Harlan, David M., Greiner, Dale L., Brehm, Michael A., Nadler, Jerry L., Wang, Jennifer P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074978/ https://www.ncbi.nlm.nih.gov/pubmed/32093375 http://dx.doi.org/10.3390/microorganisms8020295 |
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