The histone methyltransferase Setd8 alters the chromatin landscape and regulates the expression of key transcription factors during erythroid differentiation

BACKGROUND: SETD8 is the sole methyltransferase capable of mono-methylating histone H4, lysine 20. SETD8 and H4K20me1 play a role in a number of essential biologic processes, including cell cycle progression, establishment of higher order chromatin structure, and transcriptional regulation. SETD8 is...

Descripción completa

Detalles Bibliográficos
Autores principales: Myers, Jacquelyn A., Couch, Tyler, Murphy, Zachary, Malik, Jeffrey, Getman, Michael, Steiner, Laurie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075014/
https://www.ncbi.nlm.nih.gov/pubmed/32178723
http://dx.doi.org/10.1186/s13072-020-00337-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075014/
https://www.ncbi.nlm.nih.gov/pubmed/32178723
http://dx.doi.org/10.1186/s13072-020-00337-9

Ejemplares similares