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Suppression of store-operated calcium entry causes dilated cardiomyopathy of the Drosophila heart
Store-operated Ca(2+) entry (SOCE) is an essential Ca(2+) signaling mechanism present in most animal cells. SOCE refers to Ca(2+) influx that is activated by depletion of sarco/endoplasmic reticulum (S/ER) Ca(2+) stores. The main components of SOCE are STIM and Orai. STIM proteins function as S/ER C...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075072/ https://www.ncbi.nlm.nih.gov/pubmed/32086252 http://dx.doi.org/10.1242/bio.049999 |