Suppression of store-operated calcium entry causes dilated cardiomyopathy of the Drosophila heart

Store-operated Ca(2+) entry (SOCE) is an essential Ca(2+) signaling mechanism present in most animal cells. SOCE refers to Ca(2+) influx that is activated by depletion of sarco/endoplasmic reticulum (S/ER) Ca(2+) stores. The main components of SOCE are STIM and Orai. STIM proteins function as S/ER C...

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Detalles Bibliográficos
Autores principales: Petersen, Courtney E., Wolf, Matthew J., Smyth, Jeremy T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075072/
https://www.ncbi.nlm.nih.gov/pubmed/32086252
http://dx.doi.org/10.1242/bio.049999

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