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Quantitative Flow Cytometric Evaluation of Oxidative Stress and Mitochondrial Impairment in RAW 264.7 Macrophages after Exposure to Pristine, Acid Functionalized, or Annealed Carbon Nanotubes

Conventional nanotoxicological assays are subjected to various interferences with nanoparticles and especially carbon nanotubes. A multiparametric flow cytometry (FCM) methodology was developed here as an alternative to quantify oxidative stress, mitochondrial impairment, and later cytotoxic and gen...

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Detalles Bibliográficos
Autores principales: Sabido, Odile, Figarol, Agathe, Klein, Jean-Philippe, Bin, Valérie, Forest, Valérie, Pourchez, Jérémie, Fubini, Bice, Cottier, Michèle, Tomatis, Maura, Boudard, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075214/
https://www.ncbi.nlm.nih.gov/pubmed/32069806
http://dx.doi.org/10.3390/nano10020319