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The presence of the ACA box in archaeal H/ACA guide RNAs promotes atypical pseudouridylation

Archaea and eukaryotes, in addition to protein-only enzymes, also possess ribonucleoproteins containing an H/ACA guide RNA plus four proteins that produce pseudouridine (Ψ). Although typical conditions for these RNA-guided reactions are known, certain variant conditions allow pseudouridylation. We u...

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Detalles Bibliográficos
Autores principales: Majumder, Mrinmoyee, Mukhopadhyay, Shaoni, Kharel, Parinati, Gupta, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075261/
https://www.ncbi.nlm.nih.gov/pubmed/31919243
http://dx.doi.org/10.1261/rna.073734.119