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A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing

Adenosine-to-inosine RNA editing is an essential post-transcriptional modification catalyzed by adenosine deaminase acting on RNA (ADAR)1 and ADAR2 in mammals. For numerous sites in coding sequences (CDS) and microRNAs, editing is highly conserved and has significant biological consequences, for exa...

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Detalles Bibliográficos
Autores principales: Costa Cruz, Pedro Henrique, Kato, Yuki, Nakahama, Taisuke, Shibuya, Toshiharu, Kawahara, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075269/
https://www.ncbi.nlm.nih.gov/pubmed/31941663
http://dx.doi.org/10.1261/rna.072728.119