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Nanomedicines to Deliver mRNA: State of the Art and Future Perspectives

The use of messenger RNA (mRNA) in gene therapy is increasing in recent years, due to its unique features compared to plasmid DNA: Transient expression, no need to enter into the nucleus and no risk of insertional mutagenesis. Nevertheless, the clinical application of mRNA as a therapeutic tool is l...

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Detalles Bibliográficos
Autores principales: Gómez-Aguado, Itziar, Rodríguez-Castejón, Julen, Vicente-Pascual, Mónica, Rodríguez-Gascón, Alicia, Solinís, María Ángeles, del Pozo-Rodríguez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075285/
https://www.ncbi.nlm.nih.gov/pubmed/32093140
http://dx.doi.org/10.3390/nano10020364