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Nanomedicines to Deliver mRNA: State of the Art and Future Perspectives
The use of messenger RNA (mRNA) in gene therapy is increasing in recent years, due to its unique features compared to plasmid DNA: Transient expression, no need to enter into the nucleus and no risk of insertional mutagenesis. Nevertheless, the clinical application of mRNA as a therapeutic tool is l...
Autores principales: | Gómez-Aguado, Itziar, Rodríguez-Castejón, Julen, Vicente-Pascual, Mónica, Rodríguez-Gascón, Alicia, Solinís, María Ángeles, del Pozo-Rodríguez, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075285/ https://www.ncbi.nlm.nih.gov/pubmed/32093140 http://dx.doi.org/10.3390/nano10020364 |
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