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Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury
Infection with avian influenza A H5N1 virus results in acute lung injury (ALI) and has a high mortality rate (52.79%) because there are limited therapies available for treatment. Drug repositioning is an economical approach to drug discovery. We developed a method for drug repositioning based on hig...
Autores principales: | Huang, Fengming, Zhang, Cong, Liu, Qiang, Zhao, Yan, Zhang, Yuqing, Qin, Yuhao, Li, Xiao, Li, Chang, Zhou, Congzhao, Jin, Ningyi, Jiang, Chengyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075543/ https://www.ncbi.nlm.nih.gov/pubmed/32176725 http://dx.doi.org/10.1371/journal.ppat.1008341 |
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