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The immunogenicity and protective immunity of multi-epitopes DNA prime-protein  boost vaccines encoding Amastin-Kmp-11, Kmp11-Gp63 and Amastin-Gp63 against visceral leishmaniasis

Visceral leishmaniasis (VL) is the most fatal form of leishmaniasis if left untreated and 50,000 to 90,000 new cases of VL occur worldwide each year. Although various vaccines had been studied in animal models, none of them was eligible to prevent human from infections. In this study, according to t...

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Detalles Bibliográficos
Autores principales: Zhang, Jianhui, He, Jinlei, Li, Jiao, Zhou, Qi, Chen, Han, Zheng, Zhiwan, Chen, Qiwei, Chen, Dali, Chen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075555/
https://www.ncbi.nlm.nih.gov/pubmed/32176727
http://dx.doi.org/10.1371/journal.pone.0230381